Aciphex is in the class of drugs known as proton-pump inhibitors (PPIs). PPIs work to slow down the body’s production of stomach acid over a sustained period of time, helping patients with chronic or acute reflux and stomach issues.
Initially approved by the FDA in 1999, Aciphex is manufactured by Eisai, Inc., and is referred to as Pariet outside the US. Aciphex is prescribed for the maintenance and/ or treatment of ulcerative or erosive gastroesophageal reflux disease (GERD), duodenal ulcers, and pathological hypersecretory conditions.
While many PPIs are considered safe, numerous studies have linked long-term (more than one year) PPI use with serious side-effects, especially kidney malfunction.
Numerous studies have examined the efficacy and safety of PPIs like Aciphex in recent years. These studies have connected regular Aciphex use to serious adverse health events.
In 2010 the FDA warning of an increased risk of bone fractures with regular PPI use.
Late in 2014, the FDA updated Aciphex’s label to include a stronger warning of acute interstitial nephritis. This label change was corroborated by two separate studies released in 2015 and 2016. The 2015 study, published in the Canadian Medical Association Journal, found a 2.5x increase in instances of acute kidney injury among PPI users and a 3x increase in nephritis. A 2016 study at Johns Hopkins University found a 20-50% increase in chronic kidney disease for people taking PPIs over the control group.
Another study published in the Journal of the American Society of Nephrology in 2016 showed a 96% increase in kidney failure with PPI use over alternate heartburn treatments (H2-blockers). Affirming the findings from the Johns Hopkins study, this JASN study found a 26% increase in chronic kidney disease.
A 2017 study published in the peer-reviewed medical journal Gut found a 2x increased likelihood of stomach cancer for regular Aciphex takers.
Severe side-effects linked to Aciphex include:
The Combat Arms Earplug, Version 2, manufactured by 3M, was sold to the U.S. military between 2003 and 2015. The earplugs are designed as "dual-ended," allowing the user to insert them in either direc...
Accutane (also marketed as Roaccutane) is the trade or brand name for isotretinoin, a prescription drug used primarily for the treatment of severe acne. Initial experiments (in the early 1960s) consid...
Alli, the brand name for orlistat, is a prescription-grade diet pill sold over-thecounter that has been linked to embarrassing and sometimes serious side effects....
When you suffer from atrial fibrillation (known as Afib), or are otherwise at increased risk of suffering a stroke or ischemic attack, it’s a common practice for a medical professional to prescribe ...
An STEMI (ST-elevation myocardial infarction) is the medical term for a serious heart attack. It’s typically associated with a blockage in one of the main arteries leading into the heart. In most ca...
When you suffer from atrial fibrillation (known as Afib), or are otherwise at increased risk of suffering a stroke or ischemic attack, it’s a common practice for a medical professional to prescribe ...
Atorvastatin, first synthesized in the early 1980s, is a commonly prescribed pharmaceutical product used to treat high cholesterol....
The FDA released a warning on Benicar, Azor, Tribenzor, and any generic form of olmesartan medoxomil due to intestinal issues....
Hormonal contraceptives linked to heart attack, blood clots, and stroke....
There are, unfortunately, many things that can go wrong during the birth of a child. On rare occasions, the simple trauma associated with childbirth can cause injury. In most instances, though, the in...
A number of U.S. Food and Drug Administration (FDA) approved medications have been linked to increased risk of bladder or kidney cancer....
Blood pressure is an essential element of personal health. You need enough pressure to ensure that your tissue and organs get the blood they need to keep them strong and alive. However, too much press...
The U.S. Food and Drug Administration (FDA) has given approval to two different types of breast implants for sale in the United States. The breast implants both utilize an exterior silicon shell, thou...
Type 2 Diabetes remains one of the major world health problems, a leading contributor to blindness, lower limb amputation and kidney failure. Insulin has long been used in the treatment of diabetes. A...
Talcum powder is a commonly used consumer product, typically manufactured by mixing talc, a clay-based mineral, with corn starch. The powder has long been used in baby powder, by athletes to dry sweat...
When you seek treatment from a dental professional, you expect that, at a minimum, your condition won't get worse because of the wrongful acts or omissions of the dentist or dental office staff. Unfor...
Erythema multiforme, also known as EM, is a skin condition that ranges from mild rashes (erythema multiforme minor) to potentially life-threatening forms (erythema multiforme major, or EMM)....
A female sterilization/contraceptive device, Essure is a metal coil that is inserted by a physician into a woman's fallopian tubes. The insertion is performed with a catheter, and the device, once in ...
When you're experiencing health problems, one of the first things you want and need is an accurate diagnosis of the problem. Unfortunately, medical diagnostics is far from an exact science....
Created from both organic and inorganic materials, surgical mesh (most frequently used to repair hernias) comes in the form of a loosely woven sheet. It may be used for temporary or permanent support ...
A heart attack, also known as a “myocardial infarction,” is a medical condition caused by a decrease or cessation of blood flow to any part of the heart. The blockage of blood flow causes damage t...
Inferior vena cava (IVC) filters are small, cone-shaped devices that may be surgically implanted near your kidneys to impede blood clots that have broken loose from one of the deep veins in your leg (...
Invokana (also sold as Sulisent) is the trade name for canagliflozin, a pharmaceutical product approved for use in the treatment of type-2 diabetes. Canagliflozin works by inhibiting the flow of certa...
A stroke is a medical condition caused by the cessation or diminishment of the flow of blood to the brain, which causes brain cells to die. Strokes are categorized as either ischemic or hemorraghic. ...
Drug used to treat bacterial infections has been linked to severe cases of tendinitis....
Lipitor is a pharmaceutical product available only by prescription, used to treat individuals with high levels of cholesterol. It is normally considered a first-line treatment for individuals at risk ...
According to government reports, more than a million people suffer some type of adverse effect every year due to "medication errors." Those mistakes can have serious consequences, from allergic reacti...
If you have been in an accident or suffered some type of injury, you have enough to worry about without wondering how you will pay for medical care. Unfortunately, the damage caused by an accident can...
Onglyza is the trade or brand name for the drug saxagliptin, used for the treatment of diabetes. The medication was developed by Bristol-Myers Squibb and approved for sale and use by the U.S. Food and...
Opioid misuse is a severe epidemic occurring in many places across the U.S. From small towns to larger cities, opioid addiction is causing people of all walks of life significant health problems and f...
Opioids are powerful enough to affect even the most informed and responsible people. Therefore, it’s critical to have resources available to limit the effects opioid addiction can have on individual...
OxyContin, the trade name for the opioid oxycodone, was first developed in a laboratory more than 100 years ago (1916) at the University of Frankfurt, in Germany. Synthesized from thebaine, a componen...
There's a common misconception that if a drug is available "over the counter" (OTC), it must be safe and without serious side effects. That's simply not true. While, as a general rule, OTC drugs prese...
An ST-segment elevation myocardial infarction (STEMI) is the medical or technical term that doctors (primarily cardiologists) use to identify what lay persons refer to as a "heart attack." A STEMI mea...
Paxil, the brand name for paroxetine, is an SSRI mood stabilizer that has been linked to birth defects and increased suicidal thoughts and actions....
The miracles of pharmaceutical science have the potential to dramatically improve quality of life, but there are many potential pitfalls between receiving a prescription and getting it filled by a pha...
A device used to eliminate tissue from the body has been linked to the spread of cancer in hysterectomy and myomectomy patients....
Propecia (finasteride) is prescribed to treat male pattern hair loss, but over 1,400 users have filed lawsuits after experiencing long-term sexual dysfunction....
Rhabdomyolysis (also known as “rhabdo”) is a serious health condition caused by the breakdown of skeletal muscle. In worst-case scenarios, it can lead to kidney failure and even death. In most ins...
Though modern surgical advances offer hope and amazing outcomes to many people across the country, there's still a human element involved in the surgical process. Unfortunately, every year, an average...
Talcum powder is a commonly used consumer product, typically comprised of a clay-based mineral known as talc, which is mixed with corn starch. Talcum powder has been used for a variety of purposes ov...
Tequin is the brand name for the antibiotic gatifloxacin, which was banned from US markets in 2008....
Also known as Lyell or Lyell's syndrome, toxic epidermal necrolysis (TEN) first appears as a fever, mimicking many of the symptoms of the flu. Within a few days, however, a person suffering from TEN w...
Trasylol is a brand name for aprotinin, used to reduce blood loss in CPB patients, which was suspended by the FDA in 2008....
Valsartan, commonly sold under the trade name Diovan, is a pharmaceutical product marketed and sold for the treatment of high blood pressure, diabetic kidney disease, and heart failure. It was approve...
Viagra is the brand name for the well-known “little blue pill” (sildenafil citrate) used to treat male erectile dysfunction....
Xolair is the brand name for the anti-inflammatory omalizumab, primarily used in the treatment of asthma....
Zelnorm (or Zelmac) is the brand name for the IBS medication tegaserod, removed from US markets in 2007....
Zoloft (sertraline) is one of the most prescribed antidepressant SSRIs used to relieve symptoms of depression, anxiety, panic, and OCD....
Our mission at InjuredCare is to develop a family of sites that constitute the most useful, informative, reliable and exciting collection of legal resources on the web. We are constantly working to expand and improve many resources we offer to legal professionals and the public.
877-359-7077
Recording audio or video of your ex-partner in a family law case can actually backfire on you. Know your rights, and … twitter.com/i/web/status/9…11 hours ago
Are you a Dreamer? Know your rights; find a lawyer with our Attorney Directory. #InjuredCare #DACA #Dreamers … twitter.com/i/web/status/9…
Social Share